DNA Vectors
Vector Biolabs Phosphodiesterase 1C, calmodulin-dependent 70kDa Adenovirus (Ad-PDE1C)
The cyclic nucleotide phosphodiesterases (PDEs) have an important role to play in the regulation of cyclic nucleotide levels, as PDE activity hydrolyses camp and cGMP [1-5]. The PDEs are a large superfamily of enzymes consisting of eleven discovered isozyme families (PDE1-11) that differ in respect to substrate specificity, subcellular distribution and regulatory properties [2, 3, 6-9]. Of these eleven families, cGMP-activated PDE (PDE3), cAMP-specific PDE (PDE4), and the more recently discovered PDE7 and PDE8 isozymes mainly hydrolyse cAMP. The PDE5, PDE6 and PDE9 isozymes prefer cGMP as a substrate. Calcium/calmodulin-stimulated PDE (PDE1), cGMP-stimulated PDE (PDE2), PDE10 and PDE11 are dual-substrate PDEs that hydrolyse both cAMP and cGMP.
Vector Biolabs Thrombospondin 1 Adenovirus (Ad-TSP1)
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
Agilent Technologies PSHUTTLE-CMV LACZ VECTOR
PShuttle-CMV lacZ Vector is a control vector produced by insertion of the lacZ gene in the multiple cloning site of the pShuttle-CMV. This construct is provided as a control for the production of recombinant adenovirus
Vector Biolabs AAV-GFP-iCre (AAV1) AAV (AAV1-GFP-iCre)
Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cells or experimental animals.By applying the mammalian codon usage to Cre recombinase, expression of Cre is improved in the mammalian cells. This improved Cre (iCre) gene also reduce the high CpG content of the prokaryotic coding sequence, thereby reducing the chances of epigenetic silencing in mammals.This AAV1 stock expresses an improved Cre (iCre) along with eGFP under a control of the same CMV promoter. The Cre and eGFP was separated by a 2A peptides.
Vector Biolabs AAV-CAG-GFP (AAV serotype 8) AAV (AAV8-CAG-GFP)
The CAG promoter is a hybrid of the cytomegalovirus (CMV) early enhancer element and chicken beta-actin promoter. The CAG promoter is used to drive high levels of gene expression in mammalian expression vectors.This AAV serotype 8 virus (Capsid from AAV8 and ITR from AAV2) expresses eGFP (Green Fluorescent Protein) under the control of CAG promoter.
Vector Biolabs Angiopoietin 2 Adenovirus (Ad-Angiopoietin-2)
Tie2-ligand; angiopoietin-2; angiopoietin-2B; angiopoietin-2a. Naturally occurring antagonist for both ANGPT1 and TIE2; expressed only at the sites of vascular remodeling; similar to angiopoietin-1.
Vector Biolabs Adiponectin receptor 2 Adenovirus (Ad-Adipo-R2)
The adiponectin receptors, ADIPOR1 and ADIPOR2, serve as receptors for globular and full-length adiponectin and mediate increased AMPK and PPAR-alpha (PPARA) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin
Vector Biolabs AAV-CAG-GFP (AAV serotype 3) AAV (AAV3-CAG-EGFP)
The CAG promoter is a hybrid of the cytomegalovirus (CMV) early enhancer element and chicken beta-actin promoter. The CAG promoter is used to drive high levels of gene expression in mammalian expression vectors.This AAV serotype 3 virus (Capsid from AAV3 and ITR from AAV2) expresses GFP (Green Fluorescent Protein) under the control of CAG promoter.
New England Biolabs, Inc. pTYB21 Vector – 10 µg
pTYB21 is an E. coli expression N-terminal fusion vector designed for in-frame insertion of a target gene into the polylinker downstream of the intein tag. This allows the N-terminus of the target protein to be fused to the intein tag. The self-cleavage activity of the intein allows the release of the target protein from the chitin-bound intein tag, resulting in a single column purification of the target protein.
ABclonal Technology Mouse anti mCherry-Tag mAb
Protein tags are peptide sequences genetically grafted onto a recombinant protein. Often these tags are removable by chemical agents or by enzymatic means, such as proteolysis or intein splicing. Tags are attached to proteins for various purposes.Epitope tags are short peptide sequences which are chosen because high-affinity antibodies can be reliably produced in many different species. These are usually derived from viral genes, which explain their high immunoreactivity. Epitope tags include V5-tag, Myc-tag, HA-tag and NE-tag. These tags are particularly useful for western blotting, immunofluorescence and immunoprecipitation experiments, although they also find use in antibody purification.